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In differentiated CD4(+) T Cells, interleukin 4 production is cytokine-autonomous, whereas interferon γ production is cytokine-dependent

CD4(+) T cells from T cell receptor transgenic mice that have been vigorously primed to be interleukin (IL)-4 producers (T(H2) cells) are capable of producing IL-4 even if restimulated in the absence of IL-4 and in the presence of IL-12. T cells vigorously primed in the absence of IL-4 (T(H1) cells)...

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Autori principali: Hu-Li, Jane, Huang, Hua, Ryan, John, Paul, William E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1997
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC20344/
https://ncbi.nlm.nih.gov/pubmed/9096368
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