Variant estrogen receptor–c-Src molecular interdependence and c-Src structural requirements for endothelial NO synthase activation

Little is known about the tyrosine kinase c-Src's function in the systemic circulation, in particular its role in arterial responses to hormonal stimuli. In human aortic and venous endothelial cells, c-Src is indispensable for 17β-estradiol (E2)-stimulated phosphatidylinositol 3-kinase/Akt/endo...

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Bibliografiske detaljer
Main Authors: Li, Lei, Hisamoto, Koji, Kim, Kyung Hee, Haynes, M. Page, Bauer, Philip M., Sanjay, Archana, Collinge, Mark, Baron, Roland, Sessa, William C., Bender, Jeffrey R.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2007
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2034248/
https://ncbi.nlm.nih.gov/pubmed/17921256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0704315104
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