Codon 249 mutation of the p53 gene is a rare event in hepatocellular carcinomas from ethnic Chinese in Singapore.

The present study characterised p53 mutations in 44 hepatocellular carcinomas (HCCs) from Chinese patients residing in a high-incidence area. Twelve point mutations (27%) were detected in tumour tissues using single-strand conformation polymorphism analysis followed by direct DNA sequencing. Remarka...

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Main Authors: Shi, C. Y., Phang, T. W., Lin, Y., Wee, A., Li, B., Lee, H. P., Ong, C. N.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2034128/
https://ncbi.nlm.nih.gov/pubmed/7599044
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