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Carboplatin combined with amifostine, a bone marrow protectant, in the treatment of non-small-cell lung cancer: a randomised phase II study.

Amifostine (WR-2721), a thiol compound, has been shown to protect normal tissue from alkylating agents and cisplatin-induced toxicity without loss of anti-tumour effects. To confirm this result, we conducted a phase II randomised trial to determine if the addition of amifostine reduces the toxicity...

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Détails bibliographiques
Auteurs principaux: Betticher, D. C., Anderson, H., Ranson, M., Meely, K., Oster, W., Thatcher, N.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 1995
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2034079/
https://ncbi.nlm.nih.gov/pubmed/8519676
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