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Direct evidence that hydralazine can induce hypoxia in both transplanted and spontaneous murine tumours.

Hydralazine can substantially decrease blood flow and increase hypoxia in transplanted tumours. Previous indirect studies have suggested that hydralazine does not induce such effects in spontaneous tumours. We have now directly investigated the ability of hydralazine to increase hypoxia in both tran...

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Bibliographic Details
Main Authors: Horsman, M. R., Nordsmark, M., Høyer, M., Overgaard, J.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1995
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2034065/
https://ncbi.nlm.nih.gov/pubmed/8519662
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