Intra-arterial administration of the angiogenesis inhibitor TNP-470 blocks liver metastasis in a rabbit model.

We evaluated the best route of administration of TNP-470, an angiogenesis inhibitor, by comparing the anti-tumour effects and toxicity following injection via the hepatic artery, the portal vein, or the jugular vein in a rabbit model of liver metastases. Following the injections of 1 x 10(6) VX2 car...

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Autori principali: Tanaka, H., Taniguchi, H., Mugitani, T., Koishi, Y., Masuyama, M., Higashida, T., Koyama, H., Suganuma, Y., Miyata, K., Takeuchi, K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 1995
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2033903/
https://ncbi.nlm.nih.gov/pubmed/7545415
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