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Presence of a heterozygous substitution and its relationship to DT-diaphorase activity.

A point mutation in the mRNA of NADP(H): quinone oxidoreductase 1 (NQO1, DT-diaphorase) is believed to be responsible for reduced enzyme activity in the adenocarcinoma BE cell line. The present study examined nine cultured human non-cancerous fibroblast cell strains, five of which were from members...

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Autors principals: Kuehl, B. L., Paterson, J. W., Peacock, J. W., Paterson, M. C., Rauth, A. M.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1995
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2033894/
https://ncbi.nlm.nih.gov/pubmed/7669561
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