A phase II study of oral piritrexim in recurrent high-grade (III, IV) glioma.

Piritrexim is a lipid-soluble drug which is as effective an inhibitor of dihydrofolate reductase as methotrexate. Phase I and II studies have indicated activity in some tumour types. Because of its lipophilicity we have conducted a phase II study in recurrent high-grade malignant glioma (grades III...

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Detaylı Bibliyografya
Asıl Yazarlar: Bleehen, N. M., Newman, H. V., Rampling, R. P., Ramsay, J. R., Roberts, J. T., Bedford, P., Nethersell, A. B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 1995
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2033879/
https://ncbi.nlm.nih.gov/pubmed/7669591
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