Interleukin 1 and tumour necrosis factor alpha may be responsible for the lytic mechanism during anti-tumour antibody-dependent cell-mediated cytotoxicity.

Antibodies are thought to bring about tumour cell lysis by antibody-dependent cell-mediated cytotoxicity (ADCC), but the exact mechanism is not well elucidated. Monocytes are known to be important mediators of anti-tumour ADCC and are also known to secrete the cytokines tumour necrosis factor alpha...

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Main Authors: Pullyblank, A. M., Guillou, P. J., Monson, J. R.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 1995
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2033875/
https://ncbi.nlm.nih.gov/pubmed/7669568
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