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Chemokine gene transfection into tumour cells reduced tumorigenicity in nude mice in association with neutrophilic infiltration.

To study the effect of localised secretion of chemokines on tumour growth, the genes for human (hu) interleukin 8 (IL-8), hu-MCP-1 (MCAF), hu-MIP-1 alpha (LD78), murine (mu)-MCP-1 (JE), mu-MIP-1 alpha or mu-MIP-2 were introduced, via mammalian expression vectors, into Chinese hamster ovary (CHO) cel...

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Main Authors: Hirose, K., Hakozaki, M., Nyunoya, Y., Kobayashi, Y., Matsushita, K., Takenouchi, T., Mikata, A., Mukaida, N., Matsushima, K.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 1995
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2033873/
https://ncbi.nlm.nih.gov/pubmed/7669585
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