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S-phase specificity of cell killing by docetaxel (Taxotere) in synchronised HeLa cells.

Cell viability following short (1 h) contact with paclitaxel or docetaxel was assayed using synchronised HeLa cells. Docetaxel proved almost totally lethal against S-phase cells. Its toxicity was only partial against cells in mitosis, and declined to a minimum with progression to G1. For paclitaxel,...

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Bibliografische gegevens
Hoofdauteurs: Hennequin, C., Giocanti, N., Favaudon, V.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 1995
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2033844/
https://ncbi.nlm.nih.gov/pubmed/7779710
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