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Oestrogen and epidermal growth factor down-regulate erbB-2 oncogene protein expression in breast cancer cells by different mechanisms.

Mitogen-induced mammary cell growth is often accompanied by decreased levels of expression of the p185erbB-2 protein. We have previously reported that oestrogen inhibits erbB-2 mRNA and protein expression in breast cancer cells, while epidermal growth factor (EGF) treatment has been shown to decreas...

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Autori principali: Antoniotti, S., Taverna, D., Maggiora, P., Sapei, M. L., Hynes, N. E., De Bortoli, M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 1994
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2033707/
https://ncbi.nlm.nih.gov/pubmed/7526884
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