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Alteration of p53 gene in ovarian carcinoma: clinicopathological correlation and prognostic significance.

Inactivation of the tumour-suppressor gene p53 has been demonstrated in a variety of human tumours. We extracted DNA from paraffin-embedded tissues of 67 ovarian carcinoma samples (54 primary tumours, seven metastases and six tumours obtained after chemotherapy), and analysed allelic losses and muta...

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Detalhes bibliográficos
Main Authors: Niwa, K., Itoh, M., Murase, T., Morishita, S., Itoh, N., Mori, H., Tamaya, T.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1994
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2033683/
https://ncbi.nlm.nih.gov/pubmed/7981076
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