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Mechanisms of resistance to combinations of vincristine, etoposide and doxorubicin in Chinese hamster ovary cells.

We have isolated from Chinese hamster ovary cells, 30 sublines resistant to vincristine, doxorubicin or etoposide and 43 sublines evading treatment with a pair of these drugs. Isolated in one step and under low selective pressure, sublines were 3- to 25-fold more resistant to their selecting drug(s)...

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Autors principals: Souès, S., Laval, F., Charcosset, J. Y.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1995
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2033653/
https://ncbi.nlm.nih.gov/pubmed/7880729
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