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Type 1 pilus-mediated bacterial invasion of bladder epithelial cells

Most strains of uropathogenic Escherichia coli (UPEC) encode filamentous adhesive organelles called type 1 pili. We have determined that the type 1 pilus adhesin, FimH, mediates not only bacterial adherence, but also invasion of human bladder epithelial cells. In contrast, adherence mediated by anot...

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Autori principali: Martinez, Juan J., Mulvey, Matthew A., Schilling, Joel D., Pinkner, Jerome S., Hultgren, Scott J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC203355/
https://ncbi.nlm.nih.gov/pubmed/10856226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.12.2803
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