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A distal Schwann cell-specific enhancer mediates axonal regulation of the Oct-6 transcription factor during peripheral nerve development and regeneration

The POU domain transcription factor Oct-6 is a major regulator of Schwann cell differentiation and myelination. During nerve development and regeneration, expression of Oct-6 is under the control of axonal signals. Identification of the cis-acting elements necessary for Oct-6 gene regulation is an i...

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Publicat a:EMBO J
Autors principals: Mandemakers, Wim, Zwart, Ronald, Jaegle, Martine, Walbeehm, Erik, Visser, Pim, Grosveld, Frank, Meijer, Dies
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2000
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC203354/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10856243/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.12.2992
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