The effect of 5-fluorouracil and alpha interferon and 5-fluorouracil and leucovorin on cellular anti-tumour immune responses in patients with advanced colorectal cancer.

Interferon alpha (IFN-alpha) enhances the activity of 5-fluorouracil (5-FU) in the treatment of advanced colorectal cancer although the mechanism is not understood. We have investigated the effect of this combination on cellular immunity and compared this with standard therapy of 5-FU/L-leucovorin,...

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Bibliographic Details
Main Authors: Nichols, P. H., Ward, U., Ramsden, C. W., Primrose, J. N.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1994
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2033527/
https://ncbi.nlm.nih.gov/pubmed/7947102
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