Prognostic value of cytosolic tyrosine kinase activity in 249 node-positive breast cancer patients.

Tyrosine-specific protein kinase (TPK) has been associated with the cytoplasmic domain of growth factor receptors as well as oncoproteins. Enzymatic activation appears to be a major initial event in these signal transduction pathways. In this study, TPK was determined in the cytosols of 249 node-pos...

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Hauptverfasser: Romain, S., Chinot, O., Klijn, J. G., van Putten, W. L., Guirou, O., Look, M., Martin, P. M., Foekens, J. A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 1994
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2033501/
https://ncbi.nlm.nih.gov/pubmed/8054279
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