Modulation of cisplatin cytotoxicity by sulphasalazine.

The efficacy of cisplatin [cis-diamminedichloroplatinum (II); DDP] is hampered by acquired or de novo resistance of malignant cells to its cytotoxic effects. We have previously reported that cisplatin resistance parallels glutathione S-transferase (GST) activity in several human small-cell lung canc...

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Main Authors: Awasthi, S., Sharma, R., Singhal, S. S., Herzog, N. K., Chaubey, M., Awasthi, Y. C.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1994
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2033482/
https://ncbi.nlm.nih.gov/pubmed/7914420
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