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Expression of a 95 kDa membrane protein is associated with low daunorubicin accumulation in leukaemic blast cells.

A 95 kDa membrane protein (P-95) has been previously noted to be overexpressed in a doxorubicin-resistant subline of the MCF-7 breast cancer line and in clinical samples obtained from patients with solid tumours refractory to doxorubicin. We performed Western blotting on blast cell lysates from adul...

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Autori principali: Doyle, L. A., Ross, D. D., Sridhara, R., Fojo, A. T., Kaufmann, S. H., Lee, E. J., Schiffer, C. A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 1995
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2033479/
https://ncbi.nlm.nih.gov/pubmed/7819048
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