Targeted mutagenesis of Plasmodium falciparum erythrocyte membrane protein 3 (PfEMP3) disrupts cytoadherence of malaria-infected red blood cells

Adhesion of parasite-infected red blood cells to the vascular endothelium is a critical event in the pathogenesis of malaria caused by Plasmodium falciparum. Adherence is mediated by the variant erythrocyte membrane protein 1 (PfEMP1). Another protein, erythrocyte membrane protein-3 (PfEMP3), is dep...

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Autori principali: Waterkeyn, Jacqueline G., Wickham, Mark E., Davern, Kathleen M., Cooke, Brian M., Coppel, Ross L., Reeder, John C., Culvenor, Janetta G., Waller, Ross F., Cowman, Alan F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC203347/
https://ncbi.nlm.nih.gov/pubmed/10856227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.12.2813
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