Deleterious effect of serum proteins on the amphotericin B-induced potentiation of cisplatin in human colon cancer cells.

Inherent resistance of colon cancer cells to cis-diamminedichloroplatinum(II) (CDDP) is partly attributed to reduced drug penetration through plasma membrane. Amphotericin B (AmB), a polyene antifungal antibiotic, has been shown to increase CDDP penetration and cytotoxicity on several non-digestive...

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Main Authors: Assem, M., Bonvalot, S., Beltramo, J. L., Garrido, C., Dimanche-Boitrel, M. T., Genne, P., Rebibou, J. M., Caillot, D., Chauffert, B.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1994
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2033400/
https://ncbi.nlm.nih.gov/pubmed/7917908
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