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Allele loss on chromosomes 10 and 17p and epidermal growth factor receptor gene amplification in human malignant astrocytoma related to prognosis.

Patients with high-grade astrocytomas have a poor prognosis. However, considerable variation exists within this group of patients with respect to post-operative survival. In order to determine whether genetic alterations might be of help in subdividing this group, we used allele loss on chromosomes...

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Detalhes bibliográficos
Main Authors: Leenstra, S., Bijlsma, E. K., Troost, D., Oosting, J., Westerveld, A., Bosch, D. A., Hulsebos, T. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1994
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2033395/
https://ncbi.nlm.nih.gov/pubmed/7917918
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