Radioimmunotherapy of metastatic colorectal tumours with iodine-131-labelled antibody to carcinoembryonic antigen: phase I/II study with comparative biodistribution of intact and F(ab')2 antibodies.

Studies in animal tumour models of colorectal cancer suggest that F(ab')2 antibody fragments to carcinoembryonic antigen (CEA) labelled with iodine-131 give superior therapy compared with intact anti-CEA antibody. The purpose of this study was to investigate this hypothesis in patients. Ten pat...

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Main Authors: Lane, D. M., Eagle, K. F., Begent, R. H., Hope-Stone, L. D., Green, A. J., Casey, J. L., Keep, P. A., Kelly, A. M., Ledermann, J. A., Glaser, M. G.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2033373/
https://ncbi.nlm.nih.gov/pubmed/8080740
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