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Stability of the Sp3–DNA complex is promoter-specific: Sp3 efficiently competes with Sp1 for binding to promoters containing multiple Sp-sites

The transcription regulatory protein Sp3 shares more than 90% sequence homology with Sp1 in the DNA-binding domain and they bind to the same cognate DNA-element. However, the transcriptional activities of these two Sp-family factors are not equivalent. While Sp1 functions strictly as a transcription...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Principais autores: Yu, Bo, Datta, Pran K., Bagchi, Srilata
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2003
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC203306/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12954773/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg706
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