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Induction of the Generalized Shwartzman Reaction in Pregnant and Nonpregnant Rats by Colchicine

The intravenous injection of colchicine (2 mg/kg body weight) into pregnant rats on the last 4 to 5 days of gestation induced disseminated intravascular coagulation, occluding glomerular capillaries with fibrin thrombi, typical of the generalized Shwartzman reaction. Thrombi did not form earlier tha...

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Detalhes bibliográficos
Main Authors: Müller-Berghaus, Gert, Obst, Rolf
Formato: Artigo
Idioma:Inglês
Publicado em: 1972
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2032791/
https://ncbi.nlm.nih.gov/pubmed/4562795
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