A proliferation switch for genetically modified cells

Receptor dimerization is the key signaling event for many cytokines, including erythropoietin. A system has been recently developed that permits intracellular protein dimerization to be reversibly activated in response to a lipid-soluble dimeric form of the drug FK506, called FK1012. FK1012 is used...

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Bibliografiske detaljer
Main Authors: Blau, C. Anthony, Peterson, Kenneth R., Drachman, Jonathan G., Spencer, David M.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences of the USA 1997
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC20324/
https://ncbi.nlm.nih.gov/pubmed/9096348
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