Interaction of dichloromethylene diphosphonate and vitamin D on bone of thyroparathyroidectomized rats.

Dichloromethylene diphosphonate (Cl2MDP) antagonized the action of vitamin D on bone in thyroparathyroidectomized rats by reducing the metabolic activity of osteoblasts and osteocytes and decreasing the number of osteoclasts. Ultrastructurally, osteoblasts in Cl2MDP-treated rats were interpreted to...

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Main Authors: Weisbrode, S. E., Capen, C. C., Pendley, C. B.
Format: Artigo
Sprog:Inglês
Udgivet: 1977
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2032203/
https://ncbi.nlm.nih.gov/pubmed/143891
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