Disruption of the Golgi zone and inhibition of the conversion of proparathyroid hormone to parathyroid hormone in human parathyroid tissue by tris(hydroxymethyl)aminomethane.

Tris(hydroxymethyl)aminomethane (Tris, Tromethamine, THAM) and other non-amphoteric amines were previously reported to inhibit the conversion of proparathyroid hormone to parathyroid hormone in bovine parathyroid glands incubated in vitro. This inhibition correlated with a striking dilation of the G...

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Bibliographic Details
Main Authors: McGregor, D. H., Chu, L. L., MacGregor, R. R., Cohn, D. V.
Format: Artigo
Language:Inglês
Published: 1977
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2032134/
https://ncbi.nlm.nih.gov/pubmed/869014
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