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Using Support Vector Machine Regression to Model the Retention of Peptides in Immobilized Metal-affinity Chromatography

Retention of histidine-containing peptides in immobilized metal-affinity chromatography (IMAC) has been studied using several hundred model peptides. Retention in a Nickel column is primarily driven by the number of histidine residues; however, the amino acid composition of the peptide also plays a...

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Detalhes bibliográficos
Main Authors: Kermani, B. G., Kozlov, I., Melnyk, P., Zhao, C., Hachmann, J., Barker, D., Lebl, M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2031871/
https://ncbi.nlm.nih.gov/pubmed/17940590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.snb.2007.02.004
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