cAMP-mediated inhibition of the epithelial brush border Na(+)/H(+) exchanger, NHE3, requires an associated regulatory protein

NHE3 is the Na(+)/H(+) exchanger located on the intestinal and renal brush border membrane, where it functions in transepithelial Na(+) absorption. The brush border Na(+) absorptive process is acutely inhibited by activation of cAMP-dependent protein kinase, but the molecular mechanism of this inhib...

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Bibliografiska uppgifter
Huvudupphovsmän: Yun, C. H. Chris, Oh, Soohyuk, Zizak, Mirza, Steplock, Deborah, Tsao, Su, Tse, Chung-Ming, Weinman, Edward J., Donowitz, Mark
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences of the USA 1997
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC20313/
https://ncbi.nlm.nih.gov/pubmed/9096337
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