Crystal structure of desheptapeptide(B24–B30)insulin at 1.6 Å resolution: Implications for receptor binding

The crystal structure of desheptapeptide (B24–B30) insulin (DHPI), a virtually inactive analog of insulin, was determined at 1.6 Å resolution. In the refined structure model, DHPI retains three α-helices (A1–A8, A12–A18, and B9–B19) as its structural framework, while great conformational changes occ...

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Dades bibliogràfiques

Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Bao, Su-jin, Xie, Dian-lin, Zhang, Ji-ping, Chang, Wen-rui, Liang, Dong-cai
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1997
Matèries:	Biological Sciences
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20307/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9096331/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.7.2975
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