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Derivation of sarcomas from mesenchymal stem cells via inactivation of the Wnt pathway
Malignant fibrous histiocytoma (MFH), now termed high-grade undifferentiated pleomorphic sarcoma, is a commonly diagnosed mesenchymal tumor, yet both the underlying molecular mechanisms of tumorigenesis and cell of origin remain unidentified. We present evidence demonstrating that human mesenchymal...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2030456/ https://ncbi.nlm.nih.gov/pubmed/17948129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI31377 |
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