A virus-induced molecular mimicry model of multiple sclerosis

Molecular mimicry is the process by which virus infection activates T cells that are cross-reactive with self antigens. Infection of SJL/J mice with the neurotropic picornavirus Theiler’s murine encephalomyelitis virus (TMEV) leads to a progressive CD4(+) T cell–mediated demyelinating disease simila...

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Hlavní autoři: Olson, Julie K., Croxford, J. Ludovic, Calenoff, Miriam. A., Dal Canto, Mauro C., Miller, Stephen D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2001
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC203030/
https://ncbi.nlm.nih.gov/pubmed/11457884
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