Bcl-2–dependent oxidation of pyruvate dehydrogenase-E2, a primary biliary cirrhosis autoantigen, during apoptosis

The close association between autoantibodies against pyruvate dehydrogenase-E2 (PDC-E2), a ubiquitous mitochondrial protein, and primary biliary cirrhosis (PBC) is unexplained. Many autoantigens are selectively modified during apoptosis, which has focused attention on apoptotic cells as a potential...

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izdano v:	J Clin Invest
Principais autores:	Odin, Joseph A., Huebert, Robert C., Casciola-Rosen, Livia, LaRusso, Nicholas F., Rosen, Antony
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Clinical Investigation 2001
Teme:	Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC203018/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11457875/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI10716
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