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Analysis of treatment of childhood leukaemia. V. Advantage of reduced chemotherapy during and immediately after cranial irradiation.

This paper compares anti-leukaemic efficiency with toxicity to the patient of chemotherapy during and immediately after central nervous system irradiation. The drug regimen consisted of daily mercaptopurine (MP) and weekly methotrexate (MTX) at the maximum tolerated dose. Of 140 patients with acute...

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Main Authors: MacLennan, I. C., Peto, J., Kay, H. E.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 1977
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2025393/
https://ncbi.nlm.nih.gov/pubmed/412509
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