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The modification of the renal carcinogenicity of dimethylnitrosamine by actinomycin D and a protein deficient diet.

The effect of a single treatment with 30 mg dimethylnitrosamine (DMN) and 6 mug actinomycin D (ACT), given at different time intervals (ACT application to DMN, 2 h before, simultaneously, 5, 9 or 48 h later), was tested in female Sprague-Dawley rats in relation to renal carcinogenesis; additionally,...

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Detalhes bibliográficos
Main Authors: Hilfrich, J., Haas, H., Kmoch, N., Montesano, R., Mohr, U., Magee, P. N.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1975
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2024814/
https://ncbi.nlm.nih.gov/pubmed/1212416
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