A role for MEK kinase 1 in TGF-β/activin-induced epithelium movement and embryonic eyelid closure

MEKK1-deficient mice show an eye open at birth phenotype caused by impairment in embryonic eyelid closure. MEK kinase 1 (MEKK1) is highly expressed in the growing tip of the eyelid epithelium, which displays loose cell–cell contacts and prominent F-actin fibers in wild-type mice, but compact cell co...

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Main Authors: Zhang, Lin, Wang, Wei, Hayashi, Yasuhito, Jester, James V., Birk, David E., Gao, Min, Liu, Chia-Yang, Kao, Winston W.-Y., Karin, Michael, Xia, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC202382/
https://ncbi.nlm.nih.gov/pubmed/12941696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg440
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