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TLP, a novel modulator of TGF-β signaling, has opposite effects on Smad2- and Smad3-dependent signaling
Transforming growth factor-β (TGF-β) is a multifunctional cytokine signaling to the nucleus through cell surface transmembrane receptor serine/threonine kinases and cytoplasmic effectors, including Smad proteins. We describe a novel modulator of this pathway, TLP (TRAP-1-like protein), which is 25%...
Αποθηκεύτηκε σε:
Κύριοι συγγραφείς: | , , , , , , , |
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Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
Oxford University Press
2003
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC202370/ https://ncbi.nlm.nih.gov/pubmed/12941698 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg428 |
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