TLP, a novel modulator of TGF-β signaling, has opposite effects on Smad2- and Smad3-dependent signaling

Transforming growth factor-β (TGF-β) is a multifunctional cytokine signaling to the nucleus through cell surface transmembrane receptor serine/threonine kinases and cytoplasmic effectors, including Smad proteins. We describe a novel modulator of this pathway, TLP (TRAP-1-like protein), which is 25%...

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Main Authors: Felici, Angelina, Wurthner, Jens U., Parks, W.Tony, Giam, Louise Ruh-yu, Reiss, Michael, Karpova, Tatiana S., McNally, James G., Roberts, Anita B.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2003
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC202370/
https://ncbi.nlm.nih.gov/pubmed/12941698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg428
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