Modification of bacterial artificial chromosomes through Chi-stimulated homologous recombination and its application in zebrafish transgenesis

The modification of yeast artificial chromosomes through homologous recombination has become a useful genetic tool for studying gene function and enhancer/promoter activity. However, it is difficult to purify intact yeast artificial chromosome DNA at a concentration sufficient for many applications....

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Main Authors: Jessen, Jason R., Meng, Anming, McFarlane, Ramsay J., Paw, Barry H., Zon, Leonard I., Smith, Gerald R., Lin, Shuo
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 1998
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC20224/
https://ncbi.nlm.nih.gov/pubmed/9560239
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