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Construction of an expression system for engineering of the lantibiotic Pep5.

Pep5 is a lanthionine-containing antimicrobial peptide which is produced by Staphylococcus epidermidis 5. Its structural gene, pepA, is located on the 20-kb plasmid pED503. A 6.2-kb fragment of pED503 containing pepA, the immunity gene pepI, and 5.4 kb of downstream sequence was able to direct biosy...

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Main Authors: Bierbaum, G, Reis, M, Szekat, C, Sahl, H G
格式: Artigo
語言:Inglês
出版: 1994
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC201989/
https://ncbi.nlm.nih.gov/pubmed/7811073
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