Construction of an expression system for engineering of the lantibiotic Pep5.

Pep5 is a lanthionine-containing antimicrobial peptide which is produced by Staphylococcus epidermidis 5. Its structural gene, pepA, is located on the 20-kb plasmid pED503. A 6.2-kb fragment of pED503 containing pepA, the immunity gene pepI, and 5.4 kb of downstream sequence was able to direct biosy...

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Detalles Bibliográficos

Publicado en:	Appl Environ Microbiol
Autores principales:	Bierbaum, G, Reis, M, Szekat, C, Sahl, H G
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1994
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC201989/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7811073/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.60.12.4332-4338.1994
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