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Re-evaluation of pulmonary titanium dioxide nanoparticle distribution using the "relative deposition index": Evidence for clearance through microvasculature

BACKGROUND: Translocation of nanoparticles (NP) from the pulmonary airways into other pulmonary compartments or the systemic circulation is controversially discussed in the literature. In a previous study it was shown that titanium dioxide (TiO(2)) NP were "distributed in four lung compartments...

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Bibliographic Details
Main Authors: Mühlfeld, Christian, Geiser, Marianne, Kapp, Nadine, Gehr, Peter, Rothen-Rutishauser, Barbara
Format: Artigo
Language:Inglês
Published: BioMed Central 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2018701/
https://ncbi.nlm.nih.gov/pubmed/17727712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-8977-4-7
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