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A low level of reactive oxygen species selects for primitive hematopoietic stem cells that may reside in the low-oxygenic niche
A low-oxygenic niche in bone marrow limits reactive oxygen species (ROS) production, thus providing long-term protection for hematopoietic stem cells (HSCs) from ROS stress. Although many approaches have been used to enrich HSCs, none has been designed to isolate primitive HSCs located within the lo...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society of Hematology
2007
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2018677/ https://ncbi.nlm.nih.gov/pubmed/17595331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-05-087759 |
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