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Thermodynamically modulated partially double-stranded linear DNA probe design for homogeneous real-time PCR
Real-time PCR assays have recently been developed for diagnostic and research purposes. Signal generation in real-time PCR is achieved with probe designs that usually depend on exonuclease activity of DNA polymerase (e.g. TaqMan probe) or oligonucleotide hybridization (e.g. molecular beacon). Probe...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2018630/ https://ncbi.nlm.nih.gov/pubmed/17693434 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm551 |
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