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A randomized library approach to identifying functional lox site domains for the Cre recombinase

The bacteriophage P1 Cre/loxP site-specific recombination system is a useful tool in a number of genetic engineering processes. The Cre recombinase has been shown to act on DNA sequences that vary considerably from that of its bacteriophage recognition sequence, loxP. However, little is known about...

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Hlavní autoři: Sheren, Jamie, Langer, Stephen J., Leinwand, Leslie A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2018622/
https://ncbi.nlm.nih.gov/pubmed/17702764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm604
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