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Experimental support for a β-propeller domain in integrin α-subunits and a calcium binding site on its lower surface

Integrins are large, heterodimeric surface molecules of wide importance in cell adhesion. The N-terminal half of all integrin α-subunits contains seven weak sequence repeats of ≈60 amino acids that are important in ligand binding and have been predicted to fold cooperatively into a single β-propelle...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Oxvig, Claus, Springer, Timothy A.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1998
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20180/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9560195/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.9.4870
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