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Antisense oligodeoxynucleotide-mediated disruption of hippocampal cAMP response element binding protein levels impairs consolidation of memory for water maze training

Extensive evidence suggests that long term memory (LTM) formation is dependent on the activation of neuronal second messenger systems and requires protein synthesis. The cAMP response element binding protein (CREB) is a constitutively expressed regulatory transcription factor that couples changes in...

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書目詳細資料
發表在:Proc Natl Acad Sci U S A
Principais autores: Guzowski, John F., McGaugh, James L.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 1997
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在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20151/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9122258/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.6.2693
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