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Ziprasidone and the activity of cytochrome P450 2D6 in healthy extensive metabolizers

AIMS: To determine whether ziprasidone alters the metabolizing activity of the 2D6 isoenzyme of cytochrome P450 (CYP2D6). METHODS: Twenty-four healthy young subjects aged 18–45 years were screened for CYP2D6 metabolizing activity and shown to be extensive metabolizers of dextromethorphan. These subj...

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Bibliografische gegevens
Hoofdauteurs: Wilner, K D, Demattos, S B, Anziano, R J, Apseloff, G, Gerber, N
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Blackwell Science Inc 2000
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2015060/
https://ncbi.nlm.nih.gov/pubmed/10771453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2000.00152.x
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