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Influence of hydroxychloroquine on the bioavailability of oral metoprolol

AIMS: Hydroxychloroquine (HCQ) is used widely in the treatment of chronic inflammatory diseases such as rheumatoid arthritis. Since there is great interindividual variability in the pharmacokinetics of HCQ and chloroquine is a potent inhibitor of CYP2D6-catalysed pathways in vitro, we wished to stud...

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Detalhes bibliográficos
Main Authors: Somer, Mika, Kallio, Jaana, Pesonen, Ullamari, Pyykkö, Kaija, Huupponen, Risto, Scheinin, Mika
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2015042/
https://ncbi.nlm.nih.gov/pubmed/10848718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2000.00197.x
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